Stephen D. Holt., M.D.

Dr. Holt has more than 35 years of experience in Internal Medicine and Rheumatology. He has seen the field of regenerative medicine grow and develop into a far-reaching discipline which provides treatment options that heal the root cause of a patient’s pain and dysfunction. Dr. Holt is committed to providing state of the art treatments that his patients could not have even imagined at the beginning of his career. He enjoys restoring mobility, reducing pain, and improving the overall quality of his patients’ lives.
Dr. Holt developed rheumatology department at Little Rock Diagnostic Clinic, now one of the largest rheumatology practices in the U.S. He is a founding member of the Arkansas Osteoporosis Center with the first bone density measuring device. He is also a founding member of the LRDC research foundation. He lives in Denver with his wife.


Joseph A. Locke., D.O.

Dr. Locke trained at the Medical College of Wisconsin in Anesthesiology which taught him that pain is frequent and dominant in his patient’s lives. His focus is on providing pain relief solutions to patients that go above and beyond typical drug therapy or surgery. He believes that by treating the disease and not only the symptoms with Stem Cell Therapy, patients can enjoy their lives to the fullest extent.
Dr. Locke received the 2012-2014 Patients’ Choice and Compassionate Doctor Recognition Award by the online physician honor roll organization PatientsChoice.org. In addition, he is a Talk of the Town award winner for 2013 and On-Time Doctor Award recipient for 2014 exhibiting a high level of patient care.